|
KMID : 0385920220330050480
|
|
Journal of the Korean Society of Emergency Medicine
2022 Volume.33 No. 5 p.480 ~ p.486
|
|
|
Acute uncomplicated cystitis in the emergency department: prevalence of antimicrobial resistance among uropathogens and appropriate antimicrobial treatment
|
|
Chung Soo-Young
Kim Young-Sik
Jeong Ru-Bi
Lee Kyoo-Hyun
Yu Woo-Sung
Yoon Young-Tak
Choi Seung-Ju
|
|
|
Abstract
|
|
|
Objective: This study analyzed the urine cultures of emergency department patients diagnosed with acute uncomplicated cystitis and determined the antimicrobial resistance and appropriate treatment for our region.
Methods: Results of urine analysis and urine culture of acute uncomplicated cystitis patients diagnosed in our emergency department between January 2019 and December 2020 were examined and analyzed.
Results: In our study, 256 out of 340 urine culture samples (75.3%) were positive for cystitis. The most common microorganism was reported to be Escherichia coli (93.0%). The resistance rates of E. coli to the following antimicrobial agents were as follows: amikacin (0.0%), ampicillin (63.5%), amoxicillin/clavulanate (15.6%), aztreonam (7.1%), ceftazidime (3.4%), cefotaxime (16.4%), cefoxitin (5.5%), cefazolin (19.9%), ciprofloxacin (29.4%), cefepime (1.7%), ertapenem (0.0%), gentamicin (18.1%), piperacillin/tazobactam (2.1%), trimethoprim/sulfamethoxazole (36.1%), and tigecycline (0.4%). The prevalence of extended-spectrum beta-lactamase producing E. coli strains was 17.8%.
Conclusion: To determine the proper empirical antimicrobial treatment for acute uncomplicated cystitis, it is essential to examine the antimicrobial resistance. For our region, fosfomycin, nitrofurantoin, and 2nd and 3rd generation cephalosporin should be considered the first-line empirical treatment for acute uncomplicated cystitis.
|
|
|
KEYWORD
|
|
|
Cystitis, Antibiotics, Drug resistance, Emergency department
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|